| Named By: | Peter Wellnhofer in 1987 |
| Time Period: | Aptian-Albian, 112 Ma |
| Location: | Brazil - Santana Formation |
| Size: | Largest known individual based upon specimen MN 6594-1 is estimated to have had a wingspan 8.2 meters across |
| Diet: | Piscivore |
| Fossil(s): | Remains of at least three individuals, together revealing the skull and parts of the post cranial skeleton |
| Classification: | | Chordata | Reptilia | Pterosauria | Ornithocheiridae | |
| Also known as: | | Coloborhynchus mesembrinus | Criorhynchus mesembrinus | Ornithocheirus mesembrinus | |
Tropeognathus is a genus of large pterosaurs from the late Cretaceous Period of South America. It was a member of the Ornithocheiridae (alternately Anhangueridae), a group of pterosaurs known for their keel-tipped snouts, and was closely related to species of the genus Anhanguera. The type and only species is Tropeognathus mesembrinus; a second species, Tropeognathus robustus, is now considered to belong to Anhanguera.