| Named By: | Matthew in 1918 | 
| Time Period: | 20.6-13.6 Ma Early Oligocene-Early Miocene | 
| Location: | USA | 
| Size: | Estimated around 100 kilograms in weight | 
| Diet: | Carnivore | 
| Fossil(s): | Remains of many individuals | 
| Classification: | | Chordata | Mammalia | Carnivora | Caniformia | Amphicyonidae | | 
Pliocyon is genus of large amphicyonid caniformian carnivoran mammals which inhabited North America from the Early Miocene subepoch to the Middle Miocene subepoch 20.6--13.6 Ma, existing for approximately 7 million years.
Pliocyon was named by Matthew in 1918. Its type is Pliocyon medius.